uric-acid-discovery · nuki-simkin-2006-history-of-gout

In 1776 the chemical identity of uric acid was first established as a constituent of a renal calculus by the Swedish chemist Scheele, and the English chemist Woolaston demonstrated urate in a tophus from his own ear in 1797. Fifty years later, Sir Alfred Baring Garrod described his famous 'thread test' ... Garrod stated that, "the deposited urate of soda may be looked upon as the cause, and not the effect, of the gouty inflammation".