CITATION — REFERENCE ENTRY

common-core-homodimer · sadekar-2006-reaction-centers

Revision 7f645e5d-4bba-4722-bc27-652c80bf777a · 10/6/2026, 3:16:00 PM UTC
Claim ID
common-core-homodimer
Assertion
Photosynthetic reaction centers, including proteobacterial reaction centers and cyanobacterial photosystems I and II, share a conserved core of five transmembrane helices despite under 10% residual sequence identity, strongly implying common ancestry; phylogenies from structural alignments suggest the earliest reaction center was a homodimeric complex that did not evolve oxygen.
Quote
The reaction center complexes show a remarkable conservation of the core structure of 5 transmembrane helices, strongly implying common ancestry, even though the residual sequence identity is less than 10%, whereas the other proteins have structures that are unrelated. [...] Phylogenetic trees derived from the structural alignments give insights into the earliest photosynthetic reaction center, strongly suggesting that it was a homodimeric complex that did not evolve oxygen.
Quote language
en
Locator
section: Abstract
Available in