CITATION — REFERENCE ENTRY
nlrp3-initiation · poulsen-dalbeth-2025-gout-nlrp3
- Citation
- poulsen-dalbeth-2025-gout-nlrp3
- Claim ID
- nlrp3-initiation
- Assertion
- A gout flare proceeds through initiation, leucocyte mobilization and self-resolution; activation of the NLRP3 inflammasome and release of mature interleukin-1β from monocytes and macrophages is central to initiating it.
- Quote
Like all acute inflammatory responses, there are three broad stages of gout flare: initiation, leucocyte mobilization, and self-resolution. ... Activation of the NLRP3 inflammasome and release of mature interleukin-1β (IL-1β) from monocytes and macrophages is central to initiation of gout flare.
- Quote language
- en
- Locator
- section: Immune mechanisms of gout flare
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