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low-bioavailability-human-evidence-preliminary · muller-2022-aspalathin-type-2-diabetes

Revision ef35bee5-72ea-444a-b92b-cd574895068f · 10/6/2026, 4:40:29 PM UTC
Claim ID
low-bioavailability-human-evidence-preliminary
Assertion
Fermentation greatly reduces aspalathin (less than 17% remains in the processed product). Only three human bioavailability studies of aspalathin existed; in one, 0.74% of aspalathin from a green rooibos infusion was excreted in urine over 12 hours. The authors conclude that antidiabetic mechanisms are shown in cell and animal studies while human evidence remains preliminary.
Quote
The C-glycosyl parent compounds are active in cell models, but poor bioavailability would limit the therapeutic effects in vivo.
Quote language
en
Locator
section: Bioavailability and conclusions
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