CITATION — REFERENCE ENTRY
hla-b5801 · fitzgerald-2020-acr-gout-guideline
- Citation
- fitzgerald-2020-acr-gout-guideline
- Claim ID
- hla-b5801
- Assertion
- Testing for the HLA-B*5801 allele, which markedly raises the risk of allopurinol hypersensitivity, is conditionally recommended before starting allopurinol in patients of Southeast Asian descent and African American patients.
- Quote
Testing for the HLA–B*5801 allele prior to starting allopurinol is conditionally recommended for patients of Southeast Asian descent (e.g., Han Chinese, Korean, Thai) and for African American patients, over not testing for the HLA–B*5801 allele. ... The HLA–B*5801 allele is associated with a markedly elevated risk for AHS.
- Quote language
- en
- Locator
- section: Recommendations for patients receiving ULT medications: Allopurinol
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