CITATION — REFERENCE ENTRY
Conservation of distantly related membrane proteins: photosynthetic reaction centers share a common structural core — Molecular Biology and Evolution
- Key
- sadekar-2006-reaction-centers
- Authors
- Sadekar, Sumedha; Raymond, Jason; Blankenship, Robert E.
- Issued
- 2006
- Type
- article-journal
- Container
- Molecular Biology and Evolution
- Volume
- 23
- Pages
- 2001-2007
Raw CSL JSON
{
"DOI": "10.1093/molbev/msl079",
"page": "2001-2007",
"type": "article-journal",
"title": "Conservation of distantly related membrane proteins: photosynthetic reaction centers share a common structural core",
"author": [
{
"given": "Sumedha",
"family": "Sadekar"
},
{
"given": "Jason",
"family": "Raymond"
},
{
"given": "Robert E.",
"family": "Blankenship"
}
],
"issued": {
"date-parts": [
[
2006
]
]
},
"volume": "23",
"container-title": "Molecular Biology and Evolution"
}
Claims
-
Photosynthetic reaction centers, including proteobacterial reaction centers and cyanobacterial photosystems I and II, share a conserved core of five transmembrane helices despite under 10% residual sequence identity, strongly implying common ancestry; phylogenies from structural alignments suggest the earliest reaction center was a homodimeric complex that did not evolve oxygen.
"The reaction center complexes show a remarkable conservation of the core structure of 5 transmembrane helices, strongly implying common ancestry, even though the residual sequence identity is less than 10%, whereas the other proteins have structures that are unrelated. [...] Phylogenetic trees derived from the structural alignments give insights into the earliest photosynthetic reaction center, strongly suggesting that it was a homodimeric complex that did not evolve oxygen."
Available in